Two novel series of allocolchicinoids with modified seven membered B-rings: design, synthesis, inhibition of tubulin assembly and cytotoxicity

Microtubule Assembly in the Absence of Added Nucleotides

Michael L. Shelanski, Felicia Gaskin, Charles R. Cantor · Proceedings of the National Academy of Sciences · 1973 · 2.1K citations · Full text

Nucleic Acid Chemistry, Biochemistry, Natural Sciences +15

Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain

Raimond B. G. Ravelli, Benoı̂t Gigant, Patrick A. Curmi et al. · Nature · 2004 · 1.6K citations

Protein Function, Signal Transduction, Biochemistry +10

Direct conversion of activated alcohols to azides using diphenyl phosphorazidate. A practical alternative to Mitsunobu conditions

Andrew S. Thompson, Guy R. Humphrey, A. M. DEMARCO et al. · The Journal of Organic Chemistry · 1993 · 300 citations

Direct Conversion, Chemical Engineering, Chemical Measurement +9

Bicyclic and tricyclic ergoline partial structures. Rigid 3-(2-aminoethyl)pyrroles and 3- and 4-(2-aminoethyl)pyrazoles as dopamine agonists

Nicholas J. Bach, Edmund C. Kornfeld, Noel D. Jones et al. · Journal of Medicinal Chemistry · 1980 · 170 citations

Partial Structures, Organic Chemistry, Pharmacotherapy +17

THIATION WITH 2,4-BIS(4-METHOXYPHENYL)-1,3,2,4- DITHIADIPHOSPHETANE 2,4-DISULFIDE: N-METHYLTHIOPYRROLIDONE

Organic Syntheses · 1984 · 149 citations

Thiation With, Organic Chemistry, Chemistry +2