The use of leukemia inhibitory factor immobilized on virus-derived polyhedra to support the proliferation of mouse embryonic and induced pluripotent stem cells

Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors

Kazutoshi Takahashi, Shinya Yamanaka · Cell · 2006 · 26.2K citations · Full text

Tissue Engineering, Regenerative Medicine, Defined Factors +14

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

Hitoshi Niwa, Jun‐ichi Miyazaki, Austin Smith · Nature Genetics · 2000 · 3.6K citations

Embryonic Stem Cell, Cell Lineage, Quantitative Expression +9

The ground state of embryonic stem cell self-renewal

Qi‐Long Ying, Jason Wray, Jennifer Nichols et al. · Nature · 2008 · 3.5K citations · Full text

Embryonic Stem Cell, Induced Pluripotent Stem Cell, Developmental Biology +9

Epigenetic memory in induced pluripotent stem cells

K. Kim, Akiko Doi, Bo Wen et al. · Nature · 2010 · 2.3K citations · Full text

Epigenetic Memory, Chromatin, Induced Pluripotent Stem Cell +7

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

Hitoshi Niwa, Tom Burdon, Ian Chambers et al. · Genes & Development · 1998 · 1.5K citations · Full text

Regenerative Medicine, Lineage Plasticity, Induced Pluripotent Stem Cell +14