Concepedia

Gene-directed enzyme prodrug therapy (GDEPT): choice of prodrugs

C.J. Springer, Ion Niculescu‐Duvaz

Advanced Drug Delivery Reviews · 1996 · 50 citations · 42 references

DOI

Concepts

References

42

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

Kenneth W. Culver, Zvi Ram, Stuart Wallbridge et al. · Science · 1992 · 1.5K citations

, , +17

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

William S. Dynan, Robert Tjian · Nature · 1985 · 1.3K citations

, , +14

The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

Sara M. Freeman, Camille N. Abboud, Katharine A. Whartenby et al. · PubMed · 1993 · 1.1K citations

, , +10

Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy.

Frederick L. Moolten · PubMed · 1986 · 972 citations

, , +16

Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes.

Thomas K. H. Chang, Georg F. Weber, Charles L. Crespi et al. · PubMed · 1993 · 550 citations

, , +16