Concepedia

Androgen-Induced Cell Migration: Role of Androgen Receptor/Filamin A Association

Gabriella Castoria, Loredana D’Amato, Alessandra Ciociola, Pia Giovannelli, Tiziana Giraldi, Leandra Sepe, Giovanni Paolella, Maria Vittoria Barone, Antimo Migliaccio, Ferdinando Auricchio

PLoS ONE · 2011 · 102 citations · 51 references

DOIFull text

Open access

Abstract

The present report, for the first time, indicates that the extra nuclear AR/FlnA/integrin beta 1 complex is the key by which androgen activates signaling leading to cell migration. Assembly of this ternary complex may control organ development and prostate cancer metastasis.

References

51

Measurement of co‐localization of objects in dual‐colour confocal images

Erik M. M. Manders, Fons J. Verbeek, Jacob A. Aten · Journal of Microscopy · 1993 · 2.1K citations

FAK–Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

Donna J. Webb, Karen Donais, Leanna Whitmore et al. · Nature Cell Biology · 2004 · 1.4K citations

, , +11

Nongenotropic, Sex-Nonspecific Signaling through the Estrogen or Androgen Receptors

Stavroula Kousteni, Teresita Bellido, Lilian I. Plotkin et al. · Cell · 2001 · 1.1K citations · Full text

, , +8

Nongenotropic, Sex-Nonspecific Signaling through the Estrogen or Androgen Receptors Dissociation from Transcriptional Activity

S Kousteni · Cell · 2001 · 743 citations

, , +13

Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation

Antimo Migliaccio · The EMBO Journal · 2000 · 659 citations · Full text

, , +7