Concepedia

Effect of PF-04217329 a prodrug of a selective prostaglandin EP2 agonist on intraocular pressure in preclinical models of glaucoma

Ganesh Prasanna, Samantha Carreiro, Scott Anderson, Hovhannes J. Gukasyan, Soisurin Sartnurak, Husam S. Younis, David C. Gale, Cathie Xiang, Peter A. Wells, Dac M. Dinh,

Experimental Eye Research · 2011 · 66 citations · 20 references

DOI

Concepts

References

20

The advanced glaucoma intervention study (AGIS): 7. the relationship between control of intraocular pressure and visual field deterioration

American Journal of Ophthalmology · 2000 · 2.8K citations

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Phosphorylation of Glycogen Synthase Kinase-3 and Stimulation of T-cell Factor Signaling following Activation of EP2 and EP4 Prostanoid Receptors by Prostaglandin E2

Hiromichi Fujino, Kimberly A. West, John W. Regan · Journal of Biological Chemistry · 2002 · 313 citations · Full text

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Prostaglandins increase matrix metalloproteinase release from human ciliary smooth muscle cells.

Robert N. Weinreb, Kenji Kashiwagi, Fumiko Kashiwagi et al. · PubMed · 1997 · 249 citations

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Expression and localization of FP and EP prostanoid receptor subtypes in human ocular tissues.

Ursula Schlötzer‐Schrehardt, Matthias Zenkel, Rolf M. Nüsing · PubMed · 2002 · 179 citations

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Intraocular Pressure–Lowering Effects and Safety of Topical Administration of a Selective ROCK Inhibitor, SNJ-1656, in Healthy Volunteers

Hidenobu Tanihara · Archives of Ophthalmology · 2008 · 165 citations

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