Husam S. Younis

Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts

Sebastien A. Burel, Christopher E. Hart, Patrick Cauntay et al. · Nucleic Acids Research · 2015 · 200 citations · Full text

Life Sciences, Molecular Biology, Toxicology +16

Structural Basis of the Antagonism between Inorganic Mercury and Selenium in Mammals

Jürgen Gailer, Graham N. George, Ingrid J. Pickering et al. · Chemical Research in Toxicology · 2000 · 172 citations

Veterinary Medicine, Biochemistry, Toxicology +16

A Metabolic Link between Arsenite and Selenite:  The Seleno-bis(<i>S</i>-glutathionyl) Arsinium Ion

Jürgen Gailer, Graham N. George, Ingrid J. Pickering et al. · Journal of the American Chemical Society · 2000 · 146 citations

Veterinary Medicine, Biochemistry, Toxicology +16

Targeted tissue delivery of RNA therapeutics using antibody–oligonucleotide conjugates (AOCs)

Barbora Malecová, Rob S. Burke, Michael A. Cochran et al. · Nucleic Acids Research · 2023 · 137 citations · Full text

Pharmacy, Molecular Biology, Pharmacology +17

Identification and Characterization of Modified Antisense Oligonucleotides Targeting DMPK in Mice and Nonhuman Primates for the Treatment of Myotonic Dystrophy Type 1

Sanjay K. Pandey, Thurman M. Wheeler, Samantha L. Justice et al. · Journal of Pharmacology and Experimental Therapeutics · 2015 · 120 citations · Full text

Pharmacy, Molecular Biology, Molecular Medicine +17