Peter A. Wells

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

K.S. Gajiwala, Joe C. Wu, James G. Christensen et al. · Proceedings of the National Academy of Sciences · 2009 · 386 citations · Full text

Medicine, Oncology, Pharmacology +16

Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation

Tea Pemovska, Eric F. Johnson, Mika Kontro et al. · Nature · 2015 · 240 citations

Medicine, Medicinal Chemistry, Pharmacology +7

Crystal Structure of a Novel Dimeric Form of NS5A Domain I Protein from Hepatitis C Virus

Robert A. Love, Oleg Brodsky, Michael J. Hickey et al. · Journal of Virology · 2009 · 233 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Crystal Structure of the Herpes Simplex Virus 1 DNA Polymerase

Shenping Liu, John D. Knafels, Jeanne S. Chang et al. · Journal of Biological Chemistry · 2006 · 176 citations · Full text

Life Sciences, Biology, Molecular Biology +16

Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2A

Casey L. Quinlan, Stephen E. Kaiser, Ben Bolaños et al. · Nature Chemical Biology · 2017 · 132 citations

Life Sciences, Biochemistry, Medicinal Chemistry +14