Concepedia

Identification of novel inhibitors of BCR-ABL tyrosine kinase via virtual screening

Hui Peng, Niu Huang, Jing Qi, Ping Xie, Xu Chen, Jianxiang Wang, Chunzheng Yang

Bioorganic & Medicinal Chemistry Letters · 2003 · 49 citations · 13 references

DOI

Concepts

References

13

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

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Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

Brian Druker, Moshe Talpaz, Debra Resta et al. · New England Journal of Medicine · 2001 · 5.2K citations · Full text

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A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

Janet D. Rowley · Nature · 1973 · 4.3K citations

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Induction of Chronic Myelogenous Leukemia in Mice by the P210 <sup> <i>bcr/abl</i> </sup> Gene of the Philadelphia Chromosome

George Q. Daley, Richard A. Van Etten, David Baltimore · Science · 1990 · 2.2K citations · Full text

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Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase

Thomas H. Schindler, William G. Bornmann, Patricia Pellicena et al. · Science · 2000 · 1.8K citations

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