Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity

UCSF Chimera—A visualization system for exploratory research and analysis

Eric F. Pettersen, Thomas D. Goddard, Conrad C. Huang et al. · Journal of Computational Chemistry · 2004 · 47.8K citations

Computing, Bioinformatics, Visualization +17

Principal components analysis corrects for stratification in genome-wide association studies

Alkes L. Price, Nick J. Patterson, Robert M. Plenge et al. · Nature Genetics · 2006 · 10.7K citations

Public Health, Biostatistics, Genetics +12

A Unified Approach to Genotype Imputation and Haplotype-Phase Inference for Large Data Sets of Trios and Unrelated Individuals

Brian L. Browning, Sharon R. Browning · The American Journal of Human Genetics · 2009 · 1.7K citations · Full text

Public Health, Biostatistics, Genetics +14

A new model for an etiology of rheumatoid arthritis: Smoking may trigger HLA–DR (shared epitope)–restricted immune reactions to autoantigens modified by citrullination

Lars Klareskog, Patrik Stolt, Karin Lundberg et al. · Arthritis & Rheumatism · 2005 · 1.5K citations

Life Sciences, Immunology, Pathobiology +17

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

Science · 2010 · 1.2K citations · Full text

Life Sciences, Genetics, Immunology +17