Pharmacokinetics and tolerability of voriconazole and a combination oral contraceptive co‐administered in healthy female subjects

Abstract

Co-administration of voriconazole and oral contraceptive increased systemic exposures of all analytes relative to respective monotherapy. Although generally safe and well tolerated, it is recommended that patients receiving co-administered voriconazole and oral contraceptive be monitored for development of AEs commonly associated with these medications.