Hic-5 Promotes the Hypertrophic Scar Myofibroblast Phenotype by Regulating the TGF-β1 Autocrine Loop

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

Alexis Desmoulière, Antoine Geinoz, F Gabbiani et al. · The Journal of Cell Biology · 1993 · 2.2K citations · Full text

Life Sciences, Cell Biology, Pathology +14

Morphological and immunochemical differences between keloid and hypertrophic scar.

H. Paul Ehrlich, Alexis Desmoulière, Robert F. Diegelmann et al. · PubMed · 1994 · 533 citations

Medicine, Dermatology, Pathology +14

Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin

Sheila Μ. Thomas, Margit Hagel, Christopher E. Turner · Journal of Cell Science · 1999 · 157 citations

Life Sciences, Cell Biology, Molecular Biology +13

Interaction of the τ2 Transcriptional Activation Domain of Glucocorticoid Receptor with a Novel Steroid Receptor Coactivator, Hic-5, Which Localizes to Both Focal Adhesions and the Nuclear Matrix

Lan Yang, Jennifer Guerrero, Heng Hong et al. · Molecular Biology of the Cell · 2000 · 132 citations

Life Sciences, Cell Biology, Molecular Biology +17

Transforming Growth Factor- <i>beta</i> mRNA and Protein in Hypertrophic Scar Tissues and Fibroblasts: Antagonism by IFN- <i>alpha</i> and IFN- <i>gamma</i> <i>In Vitro</i> and <i>In Vivo</i>

Edward E. Tredget, Rijian Wang, Qiong Shen et al. · Journal of Interferon & Cytokine Research · 2000 · 110 citations

Veterinary Medicine, Immunology, Pathology +17