High resolution matrix‐assisted laser desorption/ionization time‐of‐flight analysis of single‐stranded DNA of 27 to 68 nucleotides in length

Noah P. Christian, Steven M. Colby, Lori Giver, Chris T. Houston, Randy J. Arnold, Andrew D. Ellington, James P. Reiily

Rapid Communications in Mass Spectrometry · 1995 · 39 citations · 31 references

Concepts

Abstract

Mass spectra of single-stranded DNA oligonucleotides were acquired using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS). Resolution enhancement using space-velocity correlation focusing allows for facile observation of different oligomers, the direct observation of individual DNA-metal adducts, and investigation of counter ion structure.

References

31