Concepedia

Kinetic Considerations for the Quantitative Assessment of Efflux Activity and Inhibition: Implications for Understanding and Predicting the Effects of Efflux Inhibition

J. Cory Kalvass, Gary M. Pollack

Pharmaceutical Research · 2006 · 107 citations · 27 references

DOI

Concepts

References

27

Passive Permeability and P-Glycoprotein-Mediated Efflux Differentiate Central Nervous System (CNS) and Non-CNS Marketed Drugs

Kelly M. Mahar Doan, Joan E. Humphreys, Lindsey O. Webster et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 626 citations

, , +17

Increased Oral Bioavailability of Topotecan in Combination With the Breast Cancer Resistance Protein and P-Glycoprotein Inhibitor GF120918

C.M.F. Kruijtzer, Jos H. Beijnen, Hilde Rosing et al. · Journal of Clinical Oncology · 2002 · 462 citations

, , +13

Increased drug delivery to the brain by P-glycoprotein inhibition

Abu Sadeque · Clinical Pharmacology & Therapeutics · 2000 · 423 citations

, , +13

Drug–drug interaction mediated by inhibition and induction of P-glycoprotein

Jiunn H. Lin · Advanced Drug Delivery Reviews · 2003 · 308 citations

, , +12

In Vitro Substrate Identification Studies for P-glycoprotein-Mediated Transport: Species Difference and Predictability of in Vivo Results

Masayo Yamazaki, William Neway, Tomoyuki Ohe et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 237 citations

, , +14