Limited contribution of CYP3A5 to the hepatic 6?-hydroxylation of testosterone

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

Medicine, Biochemistry, Pharmacology +15

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

Peter Kuehl, Jiong Zhang, Yvonne Lin et al. · Nature Genetics · 2001 · 2.2K citations

Life Sciences, Genetics, Molecular Biology +17

Characterization of Interintestinal and Intraintestinal Variations in Human CYP3A-Dependent Metabolism

Mary F. Paine, Mehraneh Khalighi, Jeannine M. Fisher et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 792 citations

Medicine, Pharmacokinetics, Pharmacology +17

The genetic determinants of the CYP3A5 polymorphism

Elisabeth Hustert, Michael Haberl, Oliver Burk et al. · Pharmacogenetics · 2001 · 670 citations

Medicine, Genetics, Molecular Genetics +13

Sex Is A Major Determinant of Cyp3a4 Expression in Human Liver

Renzo Wolbold, Kathrin Klein, Oliver Burk et al. · Hepatology · 2003 · 510 citations · Full text

Medicine, Pharmacology, Toxicology +13