Concepedia

Safety and Immunogenicity of the MRKAd5 gag HIV Type 1 Vaccine in a Worldwide Phase 1 Study of Healthy Adults

Ouzama Nicholson, Fay DiCandilo, James G. Kublin, Xiao Sun, Erin Quirk, Michelle M. Miller, Glenda Gray, Jean W. Pape, Michael Robertson, Devan V. Mehrotra,

AIDS Research and Human Retroviruses · 2010 · 23 citations · 67 references

DOI

Concepts

Abstract

vp/dose groups. Data from this first international study indicate that adenovirus-vectored vaccines are well tolerated and may be immunogenic in subjects from regions with high prevalence of preexisting Ad5 immunity.

References

67

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

Supachai Rerks‐Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan et al. · New England Journal of Medicine · 2009 · 3K citations · Full text

, , +12

Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women

Quarraisha Abdool Karim, Salim S. Abdool Karim, Janet Frohlich et al. · Science · 2010 · 2.4K citations · Full text

, , +17

Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial

Stephen Moses, Corette B. Parker, Kawango Agot et al. · The Lancet · 2007 · 2.3K citations

, , +11

Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial

Ronald H. Gray, Godfrey Kigozi, David Serwadda et al. · The Lancet · 2007 · 2.2K citations

, , +11

Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

Xueling Wu, Zhi-Yong Yang, Yuxing Li et al. · Science · 2010 · 1.8K citations

, , +17