Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice

Conduction Slowing and Sudden Arrhythmic Death in Mice With Cardiac-Restricted Inactivation of Connexin43

David E. Gutstein, Gregory E. Morley, Houman Tamaddon et al. · Circulation Research · 2001 · 685 citations · Full text

Medicine, Cardiology, Molecular Genetics +17

Increased late sodium current in myocytes from a canine heart failure model and from failing human heart

Carmen R. Valdivia, William W. Chu, Jielin Pu et al. · Journal of Molecular and Cellular Cardiology · 2005 · 444 citations

Medicine, Cardiology, Physiology +16

Activation Delay After Premature Stimulation in Chronically Diseased Human Myocardium Relates to the Architecture of Interstitial Fibrosis

Tokuhiro Kawara, Richard Derksen, Joris R. de Groot et al. · Circulation · 2001 · 386 citations

Medicine, Biomedical Sciences, Cardiology +17

Loss of Plakophilin-2 Expression Leads to Decreased Sodium Current and Slower Conduction Velocity in Cultured Cardiac Myocytes

Priscila Y. Sato, Hassan Musa, Wanda Coombs et al. · Circulation Research · 2009 · 307 citations · Full text

Medicine, Cardiology, Cell Biology +17

Slow Conduction and Enhanced Anisotropy Increase the Propensity for Ventricular Tachyarrhythmias in Adult Mice With Induced Deletion of Connexin43

Harold V.M. van Rijen, Dominik Eckardt, Joachim Degen et al. · Circulation · 2004 · 305 citations

Medicine, Cardiology, Pharmacology +16