Roel van der Nagel

MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling

Paula A. da Costa Martins, Kanita Salic, Monika M Gladka et al. · Nature Cell Biology · 2010 · 321 citations

Life Sciences, Cell Biology, Molecular Biology +10

Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency

Marina Cerrone, Maartje Noorman, Xianming Lin et al. · Cardiovascular Research · 2012 · 214 citations · Full text

Medicine, Cardiology, Molecular Genetics +17

Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice

John A. Jansen, Maartje Noorman, Hassan Musa et al. · Heart Rhythm · 2011 · 182 citations

Natural Sciences, Neuroscience, Physiology +17

Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure

Xander H.T. Wehrens, Stephan E. Lehnart, Steven Reiken et al. · Proceedings of the National Academy of Sciences · 2005 · 179 citations · Full text

Medicine, Cardiology, Pharmacology +17

NFATc2 Is a Necessary Mediator of Calcineurin-dependent Cardiac Hypertrophy and Heart Failure

Meriem Bourajjaj, Anne‐Sophie Armand, Paula A. da Costa Martins et al. · Journal of Biological Chemistry · 2008 · 164 citations · Full text

Life Sciences, Cardiology, Molecular Biology +17