Demyelination caused by the copper chelator cuprizone halts T cell mediated autoimmune neuroinflammation

mouse brain in stereotaxic coordinates

Keith B.J. Franklin, George Paxinos · 1997 · 3.1K citations

Brain Structure, Neurophysiology, Neuroanatomy +10

Immune Response in Mice that Lack the Interferon-γ Receptor

Sui Huang, Wiljan Hendriks, Alana Althage et al. · Science · 1993 · 1.6K citations · Full text

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83–99) in multiple sclerosis: Results of a phase II clinical trial with an altered peptide ligand

Bibiana Bielekova, Bonnie L. Goodwin, Nancy Richert et al. · Nature Medicine · 2000 · 819 citations

Neurodegenerative Diseases, Encephalitogenic Potential, Neurobiology Of Disease +14

Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis

Eileen McMahon, Samantha L. Bailey, Carol Vanderlugt Castenada et al. · Nature Medicine · 2005 · 678 citations

Medicine, Immunology, Immunodominance +7

Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction

Hideki Ogura, Masaaki Murakami, Yuko Okuyama et al. · Immunity · 2008 · 549 citations · Full text

Inflammation, Cytokine, Positive-feedback Loop +13