Optimisation of stabilised Carboxylesterase NP for enantioselective hydrolysis of naproxen methyl ester

A rule to predict which enantiomer of a secondary alcohol reacts faster in reactions catalyzed by cholesterol esterase, lipase from Pseudomonas cepacia, and lipase from Candida rugosa

Romas J. Kazlauskas, Alexandra N. E. Weissfloch, Aviva T. Rappaport et al. · The Journal of Organic Chemistry · 1991 · 945 citations

Life Sciences, Biochemistry, Chemistry +11

Enhancing the enantioselectivity of Candida lipase-catalyzed ester hydrolysis via noncovalent enzyme modification

Shih Hsiung Wu, Zhiwei Guo, Charles J. Sih · Journal of the American Chemical Society · 1990 · 180 citations

Life Sciences, Biochemistry, Biotechnology +16

Cross-Linked Crystals of Candida rugosa Lipase: Highly Efficient Catalysts for the Resolution of Chiral Esters

Chandrika P. Govardhan, Nazer Khalaf, Aldo G. Martinez et al. · Journal of the American Chemical Society · 1995 · 168 citations

Natural Sciences, Biochemistry, Chemistry +12

ANTI-INFLAMMATORY AND ANALGETIC PROPERTIES OF d-2-(6'-METHOXY-2'-NAPHTHYL)-PROPIONIC ACID (NAPROXEN)

Adolph P. Roszkowski, Wendell H. Rooks, A. J. TOMOLONIS et al. · Journal of Pharmacology and Experimental Therapeutics · 1971 · 147 citations

Medicine, Pharmacology, Pharmacotherapy +15

Enhancing effect of Tween-80 on lipase performance in enantioselective hydrolysis of ketoprofen ester

Youyan Liu, Jian‐He Xu, Ying Hu · Journal of Molecular Catalysis B Enzymatic · 2000 · 124 citations

Life Sciences, Biochemistry, Biotechnology +16