Jian‐He Xu

Immobilization of Serratia marcescens lipase onto amino-functionalized magnetic nanoparticles for repeated use in enzymatic synthesis of Diltiazem intermediate

Bin Hu, Jiang Pan, Hui‐Lei Yu et al. · Process Biochemistry · 2009 · 151 citations

Diltiazem Intermediate, Engineering, Biochemistry +8

Asymmetric Amination of Secondary Alcohols by using a Redox‐Neutral Two‐Enzyme Cascade

Fei‐Fei Chen, Youyan Liu, Gao‐Wei Zheng et al. · ChemCatChem · 2015 · 133 citations

Bioorganic Chemistry, Engineering, Organic Chemistry +17

Reshaping the Active Pocket of Amine Dehydrogenases for Asymmetric Synthesis of Bulky Aliphatic Amines

Fei‐Fei Chen, Gao‐Wei Zheng, Lei Liu et al. · ACS Catalysis · 2018 · 132 citations

Engineering, Aldo-keto Reductase, Molecular Biology +16

Enhancing effect of Tween-80 on lipase performance in enantioselective hydrolysis of ketoprofen ester

Youyan Liu, Jian‐He Xu, Ying Hu · Journal of Molecular Catalysis B Enzymatic · 2000 · 123 citations

Engineering, Biochemistry, Natural Sciences +9

Development of an Engineered Ketoreductase with Simultaneously Improved Thermostability and Activity for Making a Bulky Atorvastatin Precursor

Xu-Min Gong, Zhen Qin, Fulong Li et al. · ACS Catalysis · 2018 · 121 citations

Best Variant Lbcrm8, Engineering, Molecular Biology +21