Biocatalysis to amino acid-based chiral pharmaceuticals—examples and perspectives

Continuous enzymatic transformation in an enzyme membrane reactor with simultaneous NAD(H) regeneration

R. Wichmann, Christian Wandrey, Andreas F. Bückmann et al. · Biotechnology and Bioengineering · 1981 · 357 citations

Life Sciences, Bioengineering, Biotechnology +17

Enzymatic reduction of α-keto acids leading to l-amino acids, d- or l-hydroxy acids

G. Krix, Karlheinz Drauz, Matthias Kottenhahn et al. · Journal of Biotechnology · 1997 · 110 citations

Life Sciences, Biochemistry, Biocatalysis +5

Some New Developments in Reductive Amtnation with Cofactor Regeneration

Andreas S. Bommarius, Karlheinz Drauz, Werner Hummel et al. · Biocatalysis · 1994 · 75 citations

Life Sciences, Biochemistry, Microbiology +10

Enzyme-catalyzed asymmetric synthesis of (S)-2-amino-4-phenylbutanoic acid and (R)-2-hydroxy-4-phenylbutanoic acid

Curt W. Bradshaw, Chi‐Huey Wong, Werner Hummel et al. · Bioorganic Chemistry · 1991 · 53 citations

Natural Sciences, Biochemistry, Chemistry +11

Chemoenzymatic Syntheses of ω‐Ureido <scp>D</scp>‐Amino Acids

Karlheinz Drauz, Matthias Kottenhahn, Kyriakos Makryaleas et al. · Angewandte Chemie International Edition in English · 1991 · 33 citations

Life Sciences, Biochemistry, Biotechnology +11