Biocatalysis to amino acid-based chiral pharmaceuticals—examples and perspectives

Continuous enzymatic transformation in an enzyme membrane reactor with simultaneous NAD(H) regeneration

R. Wichmann, Christian Wandrey, Andreas F. Bückmann et al. · Biotechnology and Bioengineering · 1981 · 357 citations

Engineering, Cellular Enzymology, Biochemistry +14

Enzymatic reduction of α-keto acids leading to l-amino acids, d- or l-hydroxy acids

G. Krix, Karlheinz Drauz, Matthias Kottenhahn et al. · Journal of Biotechnology · 1997 · 110 citations

Engineering, Biochemistry, α-Keto Acids +8

Some New Developments in Reductive Amtnation with Cofactor Regeneration

Andreas S. Bommarius, Karlheinz Drauz, Werner Hummel et al. · Biocatalysis · 1994 · 75 citations

Keto Acid, Biosynthesis, Developmental Biology +14

Enzyme-catalyzed asymmetric synthesis of (S)-2-amino-4-phenylbutanoic acid and (R)-2-hydroxy-4-phenylbutanoic acid

Curt W. Bradshaw, Chi‐Huey Wong, Werner Hummel et al. · Bioorganic Chemistry · 1991 · 53 citations

Biosynthesis, Biochemistry, Enzyme-catalyzed Asymmetric Synthesis +2

Chemoenzymatic Syntheses of ω‐Ureido <scp>D</scp>‐Amino Acids

Karlheinz Drauz, Matthias Kottenhahn, Kyriakos Makryaleas et al. · Angewandte Chemie International Edition in English · 1991 · 33 citations

Biosynthesis, Bioorganic Chemistry, Engineering +12