Maintenance of patency after thrombolysis in stenotic coronary arteries requires combined inhibition of thrombin and platelets

Thrombolysis in Myocardial Infarction (TIMI) Trial, Phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge.

James H. Chesebro, Genell L. Knatterud, Robert Roberts et al. · Circulation · 1987 · 2.3K citations · Full text

Medicine, Cardiology, Pharmacotherapy +13

TRIAL OF TISSUE PLASMINOGEN ACTIVATOR FOR MORTALITY REDUCTION IN ACUTE MYOCARDIAL INFARCTION

Robert G. Wilcox, Carl Olsson, Allan M. Skene et al. · The Lancet · 1988 · 1.2K citations

Medicine, Cardiology, Internal Medicine +10

Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors.

Jeffrey I. Weitz, Monika Hudoba, David Massel et al. · Journal of Clinical Investigation · 1990 · 1.1K citations · Full text

Medicine, Cardiology, Pharmacology +16

Para-aminosalicylic acid in tuberculosis; early results of clinical trials.

Dempsey Tg, Logg Mh · PubMed · 1947 · 797 citations

Medicine, Infectious Diseases, Pharmacology +9

Platelet aggregation in partially obstructed vessels and its elimination with aspirin.

John D. Folts, E. B. Crowell, George G. Rowe · Circulation · 1976 · 756 citations · Full text

Medicine, Cardiology, Hematology +16