Molecular Mechanisms of Muscle Atrophy

Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy

Sue C. Bodine, Esther Latres, Susanne Baumhueter et al. · Science · 2001 · 3.4K citations · Full text

NF-κB: Ten Years After

Patrick A. Baeuerle, David Baltimore · Cell · 1996 · 3K citations · Full text

Inflammation, Autoimmune Disease, Disease Mechanism +7

Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy

Marco Sandri, Claudia Sandri, Alex Gilbert et al. · Cell · 2004 · 2.9K citations · Full text

Transcriptional Regulation, Skeletal Muscle, Genetics +6

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

Sue C. Bodine, Trevor N. Stitt, Michael Gonzalez et al. · Nature Cell Biology · 2001 · 2.7K citations

Skeletal Muscle Hypertrophy, Molecular Physiology, Muscle Injury +10

The IGF-1/PI3K/Akt Pathway Prevents Expression of Muscle Atrophy-Induced Ubiquitin Ligases by Inhibiting FOXO Transcription Factors

Trevor N. Stitt, Doreen Drujan, Brian Clarke et al. · Molecular Cell · 2004 · 1.9K citations · Full text

Muscle Function, Signaling Pathway, Cell Regulation +8