Sesquiterpene dimer (DSF-52) from Artemisia argyi inhibits microglia-mediated neuroinflammation via suppression of NF-κB, JNK/p38 MAPKs and Jak2/Stat3 signaling pathways

JAK/STAT3 pathway is activated in spinal cord microglia after peripheral nerve injury and contributes to neuropathic pain development in rat

Elisa Dominguez, Cyril Rivat, Blandine Pommier et al. · Journal of Neurochemistry · 2008 · 248 citations

Pain Medicine, Immunology, Neuropathic Pain +21

Leptin-mediated Cell Survival Signaling in Hippocampal Neurons Mediated by JAK STAT3 and Mitochondrial Stabilization

Zhihong Guo, Haiyang Jiang, X.Z. Shawn Xu et al. · Journal of Biological Chemistry · 2007 · 196 citations · Full text

Mitophagy, Apoptosis, Cell Death +24

Neuroprotective Effect of Kaempferol Glycosides against Brain Injury and Neuroinflammation by Inhibiting the Activation of NF-κB and STAT3 in Transient Focal Stroke

Lu Yu, Chu Chen, Liang-Fen Wang et al. · PLoS ONE · 2013 · 187 citations · Full text

Anti-inflammatory effects of β-lapachone in lipopolysaccharide-stimulated BV2 microglia

Dong‐Oh Moon, Yung Hyun Choi, Nam-Duk Kim et al. · International Immunopharmacology · 2007 · 180 citations

Inflammation, Lipopolysaccharide-stimulated Bv2 Microglia, Anti-inflammatory +6

Gene expression profiling of amyloid beta peptide-stimulated human post-mortem brain microglia

Douglas G. Walker · Neurobiology of Aging · 2001 · 156 citations

Alzheimer's Disease, Medicine, Dementia +11