Concepedia

Recognizing and exploiting differences between RNAi and small-molecule inhibitors

William A. Weiss, Stephen S. Taylor, Kevan M. Shokat

Nature Chemical Biology · 2007 · 293 citations · 17 references

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17

Expression profiling reveals off-target gene regulation by RNAi

Aimee L. Jackson, Steven R. Bartz, Janell M. Schelter et al. · Nature Biotechnology · 2003 · 2.4K citations

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Activation of Apoptosis in Vivo by a Hydrocarbon-Stapled BH3 Helix

Loren D. Walensky, Andrew L. Kung, Iris Escher et al. · Science · 2004 · 1.3K citations · Full text

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Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

Claire Ditchfield, Victoria Johnson, Anthony Tighe et al. · The Journal of Cell Biology · 2003 · 1.2K citations · Full text

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The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint

Silke Hauf, Richard W. Cole, Sabrina LaTerra et al. · The Journal of Cell Biology · 2003 · 1.2K citations · Full text

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A Pharmacological Map of the PI3-K Family Defines a Role for p110α in Insulin Signaling

Zachary A. Knight, Beatriz González, Morri E. Feldman et al. · Cell · 2006 · 1.2K citations · Full text

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