Concepedia
Biochemical and Biophysical Research Communications · 2006 · 14 citations · 12 references
Life SciencesCell BiologyMolecular BiologyCell DifferentiationCell SignalingGene ExpressionCell Differentiation ControlDifferentiation Signaling PathwaysMegakaryocyte DifferentiationRunx1 In Hematopoietic DevelopmentRunx1-dependent Differentiation
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AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis
Tsukasa Okuda, Jan M. van Deursen, Scott W. Hiebert et al. · Cell · 1996 · 1.9K citations · Full text
Life Sciences, Genetics, Molecular Biology +16
Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.
Qing Wang, Terryl Stacy, Michael Binder et al. · Proceedings of the National Academy of Sciences · 1996 · 1.2K citations
Life Sciences, Genetics, Molecular Genetics +14
Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
Woo‐Joo Song, Melanie G. Sullivan, Robert D. Legare et al. · Nature Genetics · 1999 · 1.1K citations
Life Sciences, Genetics, Molecular Genetics +8
AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis
Motoshi Ichikawa, Takashi Asai, Go Yamamoto et al. · Nature Medicine · 2004 · 581 citations
Life Sciences, Cell Biology, Hematology +16
Expression of the AML-1 Oncogene Shortens the G1Phase of the Cell Cycle
David K. Strom, John Nip, Jennifer J. Westendorf et al. · Journal of Biological Chemistry · 2000 · 100 citations · Full text
Life Sciences, Molecular Biology, Oncology +17