Comparative analysis of the genetic associations of HLA-DR3 and tumour necrosis factor alpha with human IDDM

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

John A. Todd, John I. Bell, Hugh O. McDevitt · Nature · 1987 · 2K citations

Medicine, Genetics, Molecular Genetics +9

THE ESTIMATION AND SIGNIFICANCE OF THE LOGARITHM OF A RATIO OF FREQUENCIES

By J. B. S. HALDANE · Annals of Human Genetics · 1956 · 1.1K citations

Business, Biostatistics, Mathematics +7

Single base polymorphism in the human Tumour Necrosis Factor alpha (TNFα) gene detectable by <i>Ncol</i> restriction of PCR product

AG Wilson, Francesco S. di Giovine, Alexandra I. F. Blakemore et al. · Human Molecular Genetics · 1992 · 892 citations

Life Sciences, Genetics, Molecular Genetics +10

An allelic polymorphism within the human tumor necrosis factor alpha promoter region is strongly associated with HLA A1, B8, and DR3 alleles.

Anthony G. Wilson, Niek de Vries, Flemming Pociot et al. · The Journal of Experimental Medicine · 1993 · 679 citations · Full text

Life Sciences, Genetics, Immunology +17

Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus.

Chaim O. Jacob, Zdenka Fronek, M Koo et al. · Proceedings of the National Academy of Sciences · 1990 · 632 citations

Life Sciences, Genetics, Immunology +17