Immune responses to all ErbB family receptors detectable in serum of cancer patients

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Medicine, Molecular Biology, Oncology +15

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

A Ullrich, Lisa M. Coussens, Joel S. Hayflick et al. · Nature · 1984 · 2.8K citations

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Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer.

José Baselga, Debu Tripathy, John Mendelsohn et al. · Journal of Clinical Oncology · 1996 · 1.4K citations

Medicine, Oncology, Pharmacology +17

Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor

Tadashi Yamamoto, Shuntaro Ikawa, Tetsu Akiyama et al. · Nature · 1986 · 1.2K citations

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<i>erb</i> B-2 Is a Potent Oncogene When Overexpressed in NIH/3T3 Cells

Pier Paolo Di Fiore, Jacalyn H. Pierce, Matthias H. Kraus et al. · Science · 1987 · 1K citations

Medicine, Molecular Biology, Oncology +14