John Mendelsohn

Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer.

José Baselga, Debu Tripathy, John Mendelsohn et al. · Journal of Clinical Oncology · 1996 · 1.4K citations

Medicine, Oncology, Pharmacology +17

Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts.

José Baselga, Larry Norton, Joan Albanell et al. · PubMed · 1998 · 1K citations

Medicine, Oncology, Pharmacology +15

Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody.

Tomoyuki Kawamoto, Jun Sato, Anh D. Le et al. · Proceedings of the National Academy of Sciences · 1983 · 796 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +16

Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model.

Neil I. Goldstein, Marie Prewett, Kazys Zuklys et al. · PubMed · 1995 · 790 citations

Medicine, Oncology, Pharmacology +14

Phase I Studies of Anti–Epidermal Growth Factor Receptor Chimeric Antibody C225 Alone and in Combination With Cisplatin

José Baselga, David G. Pfister, Michael R. Cooper et al. · Journal of Clinical Oncology · 2000 · 746 citations

Pharmacy, Oncology, Pharmacology +17