Formation of de novo centromeres and construction of first-generation human artificial microchromosomes

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector.

H. Shizuya, Bruce W. Birren, U J Kim et al. · Proceedings of the National Academy of Sciences · 1992 · 1.7K citations · Full text

Life Sciences, Biotechnology, Genetics +17

Molecular cloning of the CD2 antigen, the T-cell erythrocyte receptor, by a rapid immunoselection procedure.

Brian Seed, A Aruffo · Proceedings of the National Academy of Sciences · 1987 · 923 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans.

Gary J. Nabel, E G Nabel, Zhiyong Yang et al. · Proceedings of the National Academy of Sciences · 1993 · 890 citations

Medicine, Biotechnology, Oncology +17

Isolation of a yeast centromere and construction of functional small circular chromosomes

Louise Clarke, John Carbon · Nature · 1980 · 803 citations

Life Sciences, Genetics, Molecular Biology +14

An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2

Brian Seed · Nature · 1987 · 691 citations

Life Sciences, Immunology, Molecular Biology +9