Concepedia

Studies on the Synthesis of Apoptolidin A. 1. Synthesis of the C(1)−C(11) Fragment

Masaki Handa, Karl A. Scheidt, Martin Bossart, Nan Zheng, William Roush

The Journal of Organic Chemistry · 2007 · 44 citations · 43 references

DOI

Concepts

Abstract

A synthesis of the C(1)-C(11) fragment of apoptolidin A has been accomplished by a convergent route involving the stereoselective glycosidation of 9 and the Suzuki cross-coupling reaction of bromodienoate 7 and the vinylborane generated via chemoselective hydroboration of diyne 6 with diisopinocampheylborane.

References

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