Sprouting of the serotonergic afferents into striatum after selective lesion of the dopaminergic system by MPTP in adult mice

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Richard S. Burns, Chuang C. Chiueh, Sanford P. Markey et al. · Proceedings of the National Academy of Sciences · 1983 · 2.1K citations · Full text

Medicine, Neuroscience, Pharmacology +17

Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

J. William Langston, Lysia S. Forno, Charles S. Rebert et al. · Brain Research · 1984 · 919 citations

Medicine, Pharmacology, Toxicology +5

Reduction of cortical dopamine, noradrenaline, serotonin and their metabolites in Parkinson's disease

B. Scatton, France Javoy‐Agid, L. Rouquier et al. · Brain Research · 1983 · 725 citations

Life Sciences, Neurology, Neuroscience +12

L-Dopa: Effect on Concentrations of Dopamine, Norepinephrine, and Serotonin in Brains of Mice

G. M. Everett, James W. Borcherding · Science · 1970 · 333 citations

Medicine, Neuroscience, Pharmacology +17

An automated rotarod method for quantitative drug-free evaluation of overall motor deficits in rat models of parkinsonism

G. Rozas, María J. Guerra, José L. Labandeira‐García · Brain Research Protocols · 1997 · 291 citations

Life Sciences, Neurology, Neuroscience +14