Richard S. Burns

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Richard S. Burns, Chuang C. Chiueh, Sanford P. Markey et al. · Proceedings of the National Academy of Sciences · 1983 · 2.1K citations · Full text

Medicine, Neuroscience, Pharmacology +17

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

Sanford P. Markey, Jan N. Johannessen, Chuang C. Chiueh et al. · Nature · 1984 · 780 citations

Medicine, Neuroscience, Pharmacology +11

The Clinical Syndrome of Striatal Dopamine Deficiency

Richard S. Burns, Peter A. LeWitt, Michael H. Ebert et al. · New England Journal of Medicine · 1985 · 241 citations

Medicine, Neurology, Neuroscience +6

Neurochemical and behavioral effects of systematic and intranigral administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the rat

Chuang C. Chiueh, Sanford P. Markey, Richard S. Burns et al. · European Journal of Pharmacology · 1984 · 222 citations

Medicine, Neuroscience, Pharmacology +12

IV. Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effects

Jan N. Johannessen, Chuang C. Chiueh, Richard S. Burns et al. · Life Sciences · 1985 · 210 citations

Pharmacy, Pharmacology, Toxicology +11