Richard S. Burns

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Richard S. Burns, Chuang C. Chiueh, Sanford P. Markey et al. · Proceedings of the National Academy of Sciences · 1983 · 2.1K citations · Full text

Neurotransmitter, Neurotransmission, Social Sciences +20

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

Sanford P. Markey, Jan N. Johannessen, Chuang C. Chiueh et al. · Nature · 1984 · 779 citations

Psychoactive Drug, Neurophysiology, Medicine +10

The Clinical Syndrome of Striatal Dopamine Deficiency

Richard S. Burns, Peter A. LeWitt, Michael H. Ebert et al. · New England Journal of Medicine · 1985 · 241 citations

Neuropsychology, Nigrostriatal Dopamine Neurons, Corticobasal Degeneration +18

Neurochemical and behavioral effects of systematic and intranigral administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the rat

Chuang C. Chiueh, Sanford P. Markey, Richard S. Burns et al. · European Journal of Pharmacology · 1984 · 222 citations

Behavioral Neuroscience, Neurophysiology, Neuroanatomy +12

IV. Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effects

Jan N. Johannessen, Chuang C. Chiueh, Richard S. Burns et al. · Life Sciences · 1985 · 209 citations

Parallel Differences, Neurophysiology, Medicine +11