The Journal of Nervous and Mental Disease · 1973 · 126 citations · 0 references
MedicineNeurologyNeuroscienceBehavioral NeurologyCognitive PsychologyNeuropsychologyAlcohol DependenceAlcohol Use DisorderCognitive DisordersCognitive ImpairmentExecutive DysfunctionNeurocognitive DisordersAlcohol-related Cognitive ImpairmentAlcohol-related Neurocognitive DisordersNeurological DysfunctionPersistencePrefrontal Cortex DysfunctionWisconsin Card Sorting PerformanceWisconsin Card Sorting Test
Chronic alcoholics were administered the Wisconsin Card Sorting Test. It was found that those subjects who admitted to an alcoholism history of greater than 10 years were impaired at set persistence, set shifting, and error utilization relative to normal controls, while those subjects who described themselves as alcoholic for a period of less than 10 years were deficient in only set persistence. Neither group of alcoholics were impaired in their ability to identify simple concepts or in learning to learn capacity. The manifest behavioral deficits arc consistent with the anatomical and neurological evidence for a frontal-limbic focus of pathology in chronic alcoholism.