A radiation-controlled molecular switch for use in gene therapy of cancer

Targeted oncogene activation by site-specific recombination in transgenic mice.

Merja Lakso, Brian Sauer, B Mosinger et al. · Proceedings of the National Academy of Sciences · 1992 · 693 citations

Medicine, Genetics, Molecular Biology +17

Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase

Yumi Kanegae, Gwang Lee, Yumi Sato et al. · Nucleic Acids Research · 1995 · 613 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1.

M.J. Wagner, J A Sharp, William C. Summers · Proceedings of the National Academy of Sciences · 1981 · 390 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Spatial and temporal control of gene therapy using ionizing radiation

Dennis E. Hallahan, Helena J. Mauceri, Lisa P. Seung et al. · Nature Medicine · 1995 · 316 citations

Medicine, Oncology, Radiation Oncology +14

Cre-stimulated recombination at<i>loxP</i>-containing DNA sequences placed into the mammalian genome

Brian Sauer, Nancy Henderson · Nucleic Acids Research · 1989 · 265 citations · Full text

Life Sciences, Genetics, Molecular Biology +17