GP Margison

Depletion of O6-alkylguanine-DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumour cells

J Baer, E.S. Newlands, GP Margison · British Journal of Cancer · 1993 · 198 citations · Full text

Medicine, Oncology, Pharmacology +14

Reduction of the toxicity and mutagenicity of alkylating agents in mammalian cells harboring the Escherichia coli alkyltransferase gene.

John Brennand, GP Margison · Proceedings of the National Academy of Sciences · 1986 · 125 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Levels of the DNA repair enzyme human apurinic/apyrimidinic endonuclease (APE1, APEX, Ref-1) are associated with the intrinsic radiosensitivity of cervical cancers

C J Herring, DP Wilks, S.E. Davidson et al. · British Journal of Cancer · 1998 · 96 citations

Medicine, Molecular Biology, Oncology +14

O6-Methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma

MR Middleton, JM Lunn, C. Morris et al. · British Journal of Cancer · 1998 · 86 citations · Full text

Medicine, Molecular Biology, Oncology +14

Development of synthetic promoters for radiation-mediated gene therapy

Brian Marples, Simon D. Scott, J H Hendry et al. · Gene Therapy · 2000 · 79 citations

Medicine, Molecular Biology, Radiation Oncology +14