Concepedia

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3–mediated interferon-β induction

Hiroyuki Oshiumi, Misako Matsumoto, Kenji Funami, Takashi Akazawa, Tsukasa Seya

Nature Immunology · 2003 · 1.2K citations · 37 references

Concepts

Life SciencesImmunologyMolecular BiologyCell SignalingInnate ImmunitySignal TransductionAdaptor ProteinsInflammatory SignalingInnate Immune ReceptorsInnate Immune ResponseInnate Immune Signaling PathwaysToll-like ReceptorsToll-like Receptor SignalingToll-like Receptor Signaling PathwaysToll-like Receptor-mediated Cytokine InductionToll-like Receptor-mediated Innate Immune ResponseToll-like Receptors In InflammationType I Interferon InductionType I Interferon Pathways

References

37

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.4K citations

Life Sciences, Molecular Biology, Molecular Genetics +7

A Toll-like receptor recognizes bacterial DNA

Hiroaki Hemmi, Osamu Takeuchi, Taro Kawai et al. · Nature · 2000 · 6.4K citations

Life Sciences, Immunology, Microbiology +13

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Lena Alexopoulou, Agnieszka Czopik Holt, Ruslan Medzhitov et al. · Nature · 2001 · 6.1K citations

Life Sciences, Immunology, Molecular Biology +14

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Ruslan Medzhitov, Paula Preston‐Hurlburt, Charles A. Janeway · Nature · 1997 · 5.5K citations

Life Sciences, Immunology, Molecular Biology +13

Methods in Yeast Genetics

Heiner Jacob · Bioelectrochemistry and Bioenergetics · 1988 · 4.9K citations

Life Sciences, Biology, Genetics +11