Development of pharmacodynamic tolerance to prazosin in congestive heart failure

THE RENAL CLEARANCES OF SUBSTITUTED HIPPURIC ACID DERIVATIVES AND OTHER AROMATIC ACIDS IN DOG AND MAN 1

Homer W. Smith, N.P. Finkelstein, Lucy Aliminosa et al. · Journal of Clinical Investigation · 1945 · 1.6K citations · Full text

Sustained Reduction of Cardiac Impedance and Preload in Congestive Heart Failure with the Antihypertensive Vasodilator Prazosin

Richard R. Miller, Najam A. Awan, Kevin S. Maxwell et al. · New England Journal of Medicine · 1977 · 262 citations

Hemodynamic and clinical tachyphylaxis to prazosin-mediated afterload reduction in severe chronic congestive heart failure.

Milton Packer, Jose Meller, R Gorlin et al. · Circulation · 1979 · 243 citations · Full text

Efficacy of ambulatory systemic vasodilator therapy with oral prazosin in chronic refractory heart failure. Concomitant relief of pulmonary congestion and elevation of pump output demonstrated by improvements in symptomatology, exercise tolerance, hemodynamics and echocardiography.

Najam A. Awan, Richard R. Miller, Anthony N. DeMaria et al. · Circulation · 1977 · 174 citations · Full text

Hypertension, Heart Failure, Cardiovascular Pharmacology +21

Effect of prazosin vs placebo on chronic left ventricular heart failure.

Wilbert S. Aronow, Mark Lurie, Marvin Turbow et al. · Circulation · 1979 · 113 citations · Full text

Hypertension, Heart Failure, Device Therapy +16