Concepedia

Recombinant Liver Stage Antigen-1 (LSA-1) formulated with AS01 or AS02 is safe, elicits high titer antibody and induces IFN-γ/IL-2 CD4+ T cells but does not protect against experimental Plasmodium falciparum infection

James F. Cummings, Michele Spring, Robert Schwenk, Christian F. Ockenhouse, Kent E. Kester, Mark E. Polhemus, Douglas S. Walsh, In‐Kyu Yoon, Christine Prosperi, Laure Juompan,

Vaccine · 2009 · 88 citations · 33 references

DOI

Concepts

References

33

Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

Patricia A. Darrah, Dipti T. Patel, Paula Mello De Luca et al. · Nature Medicine · 2007 · 1.4K citations

, , +14

Molecular analysis of the association of HLA-B53 and resistance to severe malaria

Adrian V. S. Hill, John Elvin, Anthony C. Willis et al. · Nature · 1992 · 643 citations

, , +10

Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans

Samuel McConkey, William H. H. Reece, Vasee Moorthy et al. · Nature Medicine · 2003 · 558 citations

, , +16

Randomized, Double‐Blind, Phase 2a Trial of Falciparum Malaria Vaccines RTS,S/AS01B and RTS,S/AS02A in Malaria‐Naive Adults: Safety, Efficacy, and Immunologic Associates of Protection

Kent E. Kester, James F. Cummings, Opokua Ofori‐Anyinam et al. · The Journal of Infectious Diseases · 2009 · 538 citations · Full text

, , +17

Interleukin-10 production by effector T cells: Th1 cells show self control

Giorgio Trinchieri · The Journal of Experimental Medicine · 2007 · 371 citations · Full text

, , +17