Concepedia

Dynamics of macrophage polarization reveal new mechanism to inhibit IL‐1β release through pyrophosphates

Pablo Pelegrı́n, Annmarie Surprenant

The EMBO Journal · 2009 · 259 citations · 31 references

DOIFull text

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Concepts

References

31

The Inflammasome

Fabio Martinon, Kimberly Burns, Jürg Tschopp · Molecular Cell · 2002 · 6K citations · Full text

Gout-associated uric acid crystals activate the NALP3 inflammasome

Fabio Martinon, Virginie Pétrilli, Annick Mayor et al. · Nature · 2006 · 5.2K citations

, , +11

Biologic basis for interleukin-1 in disease

CA Dinarello · Blood · 1996 · 4.4K citations · Full text

, , +12

Cryopyrin activates the inflammasome in response to toxins and ATP

Sanjeev Mariathasan, David S. Weiss, Kim Newton et al. · Nature · 2006 · 3K citations

, , +7

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung, Franz Bauernfeind, Annett Halle et al. · Nature Immunology · 2008 · 3K citations · Full text

, , +13