Mathematically modeling dynamics of T cell responses: Predictions concerning the generation of memory cells

A Simplex Method for Function Minimization

J. A. Nelder, R. Mead · The Computer Journal · 1965 · 28.5K citations

Numerical Analysis, Mathematical Programming, Large-scale Global Optimization +16

Lineage relationship and protective immunity of memory CD8 T cell subsets

E. John Wherry, Volker Teichgräber, Todd C. Becker et al. · Nature Immunology · 2003 · 1.8K citations · Full text

Protective Immunity, Autoimmune Disease, Adaptive Immune System +9

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

Susan M. Kaech, Rafi Ahmed · Nature Immunology · 2001 · 1.3K citations · Full text

Developmental Biology, Autoimmune Disease, Lymphocyte Development +12

Molecular and Functional Profiling of Memory CD8 T Cell Differentiation

Susan M. Kaech, Scott E. Hemby, Ellen N. Kersh et al. · Cell · 2002 · 967 citations · Full text

Lymphocyte Development, T-regulatory Cell, Immunology +7

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

Marianne J.B. van Stipdonk, Edward E. Lemmens, Stephen P. Schoenberger · Nature Immunology · 2001 · 843 citations

Naïve Ctls, Single Brief Period, Signal Transduction +10