Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages

Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

Fan Yeung, Jamie E. Hoberg, C S Ramsey et al. · The EMBO Journal · 2004 · 2.6K citations · Full text

The Human Sir2 Ortholog, SIRT2, Is an NAD+-Dependent Tubulin Deacetylase

Brian J. North, Brett Marshall, Margie T. Borra et al. · Molecular Cell · 2003 · 1.5K citations · Full text

Signal Transduction, Cellular Enzymology, Biochemistry +7

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

Tiara L.A. Kawahara, Eriko Michishita, Adam S. Adler et al. · Cell · 2009 · 1.1K citations · Full text

Histone Modifications, Chromatin, Transcriptional Regulation +15

MAPKAP kinase 2 is essential for LPS-induced TNF-α biosynthesis

Alexey Kotlyarov, Armin Neininger, Carola Schubert et al. · Nature Cell Biology · 1999 · 755 citations

Signal Transduction, Signaling Pathway, Mapkap Kinase 2 +4

p38-dependent marking of inflammatory genes for increased NF-κB recruitment

Simona Saccani, Serafino Pantano, Gioacchino Natoli · Nature Immunology · 2001 · 689 citations

Inflammation, Cytokine, Inflammatory Genes +10