Interleukin-12 enhances the virus-specific interferon gamma response of pigs to an inactivated pseudorabies virus vaccine

Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming.

R A Seder, Ricardo T. Gazzinelli, Ali Sher et al. · Proceedings of the National Academy of Sciences · 1993 · 981 citations

Life Sciences, Cell Biology, Immunology +17

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

Catherine S. Tripp, S F Wolf, Emil R. Unanue · Proceedings of the National Academy of Sciences · 1993 · 781 citations · Full text

Life Sciences, Immunology, Microbiology +17

The Adjuvant Effect of Interleukin-12 in a Vaccine Against <i>Leishmania major</i>

Luís Afonso, Tanya M. Scharton, Leda Quércia Vieira et al. · Science · 1994 · 682 citations

Veterinary Medicine, Immunology, Infectious Diseases +17

Effects of IL-12 on helper T cell-dependent immune responses in vivo.

Áine McKnight, G J Zimmer, I. Fogelman et al. · The Journal of Immunology · 1994 · 289 citations · Full text

Life Sciences, Immunology, Adaptive Immunity +16

Functional and phenotypic analysis of porcine peripheral blood CD4/CD8 double-positive T cells.

Federico A. Zuckermann, Robert J. Husmann · PubMed · 1996 · 265 citations

Life Sciences, Immunology, Cellular Immunology +16