R A Seder

Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming.

R A Seder, Ricardo T. Gazzinelli, Ali Sher et al. · Proceedings of the National Academy of Sciences · 1993 · 978 citations

Interferon Gamma Production, Adaptive Immune System, Priming Process +19

Activation events during thymic selection.

Albert Bendelac, Polly Matzinger, R A Seder et al. · The Journal of Experimental Medicine · 1992 · 319 citations · Full text

Lymphocyte Development, T-regulatory Cell, Immunology +17

Anti-IL-4 treatment of <i>Schistosoma mansoni</i> -infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis.

Allen W. Cheever, Megan E. Williams, Thomas A. Wynn et al. · The Journal of Immunology · 1994 · 273 citations · Full text

Factors involved in the differentiation of TGF-beta-producing cells from naive CD4+ T cells: IL-4 and IFN-gamma have opposing effects, while TGF-beta positively regulates its own production.

R A Seder, Thomas Marth, M C Sieve et al. · PubMed · 1998 · 203 citations

Adaptive Immune System, T-regulatory Cell, Immunology +16

Cytokine interactions in human immunodeficiency virus-infected individuals: roles of interleukin (IL)-2, IL-12, and IL-15.

R A Seder, Kenneth H. Grabstein, J A Berzofsky et al. · The Journal of Experimental Medicine · 1995 · 113 citations · Full text

Cytokine Interactions, Immunology, Immune Regulation +17