Alkylation of chiral prolinol propionamide enolates with epoxides: Complete reversal of predicted facial selectivity

.alpha.-Methoxy-.alpha.-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines

James A. Dale, David L. Dull, Harry S. Mosher · The Journal of Organic Chemistry · 1969 · 2.5K citations

Natural Sciences, Chemistry, Analytical Chemistry +6

Structure of FK506, a novel immunosuppressant isolated from Streptomyces

Hirokazu Tanaka, Akio Kuroda, Hiroshi Marusawa et al. · Journal of the American Chemical Society · 1987 · 514 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8

Reactions that proceed with a combination of enantiotopic group and diastereotopic face selectivity can deliver products with very high enantiomeric excess: experimental support of a mathematical model

Stuart L. Schreiber, Thomas S. Schreiber · Journal of the American Chemical Society · 1987 · 210 citations

Natural Sciences, Chemistry, Catalysis +6

Enantioselective alkylation of chiral enolates

David A. Evans, James M. Takacs · Tetrahedron Letters · 1980 · 174 citations

Natural Sciences, Chemistry, Catalysis +5

Acyclic stereoselection. 11. Double stereodifferentiation as a method for achieving superior Cram's rule selectivity in aldol condensations with chiral aldehydes

Clayton H. Heathcock, Charles T. White, James Jeffery Morrison et al. · The Journal of Organic Chemistry · 1981 · 123 citations

Natural Sciences, Chemistry, Catalysis +11