D. Askin

Highly diastereoselective alkylations of chiral amide enolates: new routes to hydroxyethylene dipeptide isostere inhibitors of HIV-1 protease

D. Askin, M A Wallace, Joseph P. Vacca et al. · The Journal of Organic Chemistry · 1992 · 195 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6

Total synthesis of immunosuppressant (-)-FK-506

Todd K. Jones, Sander G. Mills, Robert A. Reamer et al. · Journal of the American Chemical Society · 1989 · 151 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Asymmetric hydrogenation of tetrahydropyrazines: Synthesis of (S)-piperazine-2-tert-butylcarboxamide, an intermediate in the preparation of the HIV protease inhibitor indinavir

Kai Rossen, Steven A. Weissman, Jess W. Sager et al. · Tetrahedron Letters · 1995 · 113 citations

Pharmacy, Chemistry, Medicinal Chemistry +14

Diastereoselective syn-epoxidation of 2-alkyl-4-enamides to epoxyamides: Synthesis of the Merck HIV-1 protease inhibitor epoxide intermediate

Peter E. Maligres, Veena Upadhyay, Kai Rossen et al. · Tetrahedron Letters · 1995 · 69 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8

Synthesis of a branched cyclic peptide using a strategy employing Fmoc chemistry and two additional orthogonal protecting groups

Graham B. Bloomberg, D. Askin, A.R. Gargaro et al. · Tetrahedron Letters · 1993 · 59 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11