Expression of integrins α3β1 and α5β1 and GlcNAc β1,6 glycan branching influences metastatic melanoma cell migration on fibronectin

VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

Rosandra N. Kaplan, Rebecca D. Riba, Stergios Zacharoulis et al. · Nature · 2005 · 3.2K citations · Full text

Pre-metastatic Niche, Stem Cell Mobilization, Biological Microenvironments +4

Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

Filippo G. Giancotti, Erkki Ruoslahtl · Cell · 1990 · 747 citations

α5β1 Fibronectin Receptor, Developmental Biology, Signal Transduction +11

Suppression of tumor growth and metastasis in Mgat5-deficient mice

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Medicine, Tumor Growth, Tumor Suppressor +4

Aberrant N-glycosylation of beta1 integrin causes reduced alpha5beta1 integrin clustering and stimulates cell migration.

Hua‐Bei Guo, Intaek Lee, Maria Kamar et al. · PubMed · 2002 · 280 citations

Cell Adhesion, Glycobiology, Pathology +20

Aberrant glycosylation associated with enzymes as cancer biomarkers

Daniel W. Chan · Clinical Proteomics · 2011 · 258 citations · Full text