Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells

HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS

Michael N. Berry, Daniel S. Friend · The Journal of Cell Biology · 1969 · 4.4K citations · Full text

Life Sciences, Biochemistry, Cell Biology +7

Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes

Umut Özcan, Qiong Cao, Erkan Yılmaz et al. · Science · 2004 · 3.8K citations

Life Sciences, Endocrinology, Molecular Biology +17

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease

Kerry L. Donnelly, Coleman I. Smith, Sarah Jane Schwarzenberg et al. · Journal of Clinical Investigation · 2005 · 3.5K citations · Full text

Life Sciences, Biochemistry, Nutritional Sciences +17

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

Ole Thastrup, Peter J. Cullen, Bjørn K. Drøbak et al. · Proceedings of the National Academy of Sciences · 1990 · 3.3K citations

Life Sciences, Cell Biology, Pharmacology +15

Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes

Umut Özcan, Erkan Yılmaz, Lale Özcan et al. · Science · 2006 · 2.4K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17