α2-adrenoceptor coupling to adenylate cyclase in adrenaline insensitive human platelets

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

Peter J. Munson, David Rodbard · Analytical Biochemistry · 1980 · 8.5K citations

Life Sciences, Chemistry, Biomolecular Modeling +11

Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal

G. V. R. Born · Nature · 1962 · 4.3K citations

Medicine, Biochemistry, Hematology +14

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

André DeLÉAN, Peter J. Munson, David Rodbard · American Journal of Physiology-Endocrinology and Metabolism · 1978 · 2.4K citations

Medicine, Biostatistics, Pharmacology +17

A simple and sensitive saturation assay method for the measurement of adenosine 3′:5′-cyclic monophosphate

B. L. Brown, J. D. M. Albano, Roger Ekins et al. · Biochemical Journal · 1971 · 1.5K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +7