A major role for Mcl-1 antiapoptotic protein in the IL-6-induced survival of human myeloma cells

Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

Robyn Catlett-Falcone, Terry H. Landowski, Marc M. Oshiro et al. · Immunity · 1999 · 1.6K citations · Full text

Cell Regulation, Constitutive Activation, Medicine +8

Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6

Bernard Klein, XG Zhang, M Jourdan et al. · Blood · 1989 · 755 citations · Full text

Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

Pearlie K. Epling‐Burnette, Jin Hong Liu, Robyn Catlett-Falcone et al. · Journal of Clinical Investigation · 2001 · 642 citations · Full text

IgG1 plasmacytosis in interleukin 6 transgenic mice.

S Suematsu, T Matsuda, Katsuyuki Aozasa et al. · Proceedings of the National Academy of Sciences · 1989 · 594 citations · Full text

Inflammation, Cytokine, Immunogenetics +15

Activation of NF-κB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications

Constantine S. Mitsiades, Nicholas Mitsiades, Vassiliki Poulaki et al. · Oncogene · 2002 · 460 citations

Inflammation, Cancer Research, Igf-1/akt Signaling +12